The above findings are highly significant, showing that resveratrol blocks the acquisition of epithelial tumor cell motility by: (i) Suppressing HGF expression and secretion from cultured PrSC, and (ii) disrupting HGF signaling events in epithelial tumor cells.
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Resveratrol Suppresses Prostate Cancer Epithelial Cell Scatter/Invasion by Targeting Inhibition of Hepatocyte Growth Factor (HGF) Secretion by Prostate Stromal Cells and Upregulation of E-cadherin by Prostate Cancer Epithelial Cells.
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