Barely Significant
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Codon usage pattern and its influencing factors in different genomes of hepadnaviruses.

Arch Virol · 2020 · PMC7086886 · PMID 32036428

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highly significantp < 0.01actually significant
A highly significant correlation was observed between GC12 and GC3 (r = 0.910, p < 0.01), indicating that directional mutation affected all three codon positions across the genome.

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