Scientific barriers to developing vaccines against avian influenza viruses.

Nat Rev Immunol · 2007 · PMC7097526 · PMID 17363960

Europe PMC DOI

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might not be significantno p-value reported

Also, changes in the virus that are driven by positive immune selection in poultry might not be significant in humans.

also in 673 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.