Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes.

J Neuroinflammation · 2020 · PMC7098135 · PMID 32213184

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highly significantno p-value reported

After 2 days of administering LPS, there was a highly significant increase in both the proportion of CD45 hi cells (7.2-fold) and CD45 transcript levels (3.7-fold) in the brain compared with PBS-treated controls (Supplementary Figure 3 B-D).

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