Heart Failure with Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women.

JACC Case Rep · 2020 · PMC7100876 · PMID 32226944

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

narrowly missed statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

Although the trial narrowly missed statistical significance in the primary composite outcome (total hospitalization for HF and cardiovascular death; p = 0.059); in a pre-specified subgroup analysis, there was a significant reduction in the primary composite outcome in women (incidence rate ratio: 0.73; 95% confidence interval: 0.59 to 0.90).

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