highly significantP = 4.7 × 10 −103
We also confirmed strong and highly significant associations at the previously described loci, including chromosome 2q24.2 encoding PLA2R1 (rs17831251, OR = 2.25, Meta-analysis P = 4.7 × 10 −103 ) and 6p21.32 encoding HLA-DQA1/DRB1 genes (rs9271573, OR = 2.41, Meta-analysis P = 2.7 × 10 −154 ).