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The Impact of Changes in Clinical Guideline on Practice Patterns and Healthcare Utilizations for Kawasaki Disease in Japan.

Front Pediatr · 2020 · PMC7105796 · PMID 32266191

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a decreasing trendno p-value reported
Correspondingly, the risks of CALs showed a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported
The spline model showed an increasing trend in glucocorticoid use during the initial phase that started in January 2012 and leveled off after March 2013 ( Figure 1 ).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.