However, at 72 h, late apoptotic cells (AV/PI double positive) showed a similar, highly significant difference between Ov8.25-transfected cells without and Ov8.25-transfected cells with caspase inhibitors or EYFP-transfected cells, independent of the presence or absence of inhibitors ( Fig. 13E ).
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Ovine Herpesvirus 2 Encodes a Previously Unrecognized Protein, pOv8.25, That Targets Mitochondria and Triggers Apoptotic Cell Death.
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