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Modeling the adaptive immune system: predictions and simulations.

Bioinformatics · 2007 · PMC7110254 · PMID 18045832

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highly significantno p-value reported
Integrating the dynamic (using mathematical models and computer simulations) and bioinformatics approaches clearly could lead to a better understanding of the immune responses and their role during normal, disease and reconstitution states, where both timing and sequence specificity are highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.