Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection.

39 Therefore, although the highly significant associations between CCL2 G-2518A and susceptibility to SARS-CoV infection were biologically plausible, and strengthened by our 4 independent case–control studies, it remains interesting to investigate that whether there exist population-specific differences for this polymorphism to SARS susceptibility between Chinese and Europeans.

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