Major surgery induces acute changes in measured DNA methylation associated with immune response pathways.

Compared to baseline we observed a highly significant increase in both serum CRP (baseline: median CRP = 6.0 mg/l; POD1: median CRP = 52 mg/l, P = 4.55E-03) (Fig. 1A ) and IL-6 (baseline: median IL-6 = 6.6 pg/ml; POD1: median IL-6 = 121.7 pg/ml, P = 7.23E-06) (Fig. 1B ) at POD1.

also in 132,142 other papers