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Experimental Treatment of SIV-Infected Macaques via Autograft of <i>CCR5</i>-Disrupted Hematopoietic Stem and Progenitor Cells.

Mol Ther Methods Clin Dev · 2020 · PMC7114624 · PMID 32258215

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a decreasing trendno p-value reported
When hematopoietic mobilization was performed and PBMCs were collected by apheresis, the absolute counts of CD4 + T cells showed a decreasing trend from the second collection of HSPCs 4 months before the operation and declined to the nadir after the injection of busulfan ( Figure 7 A).

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