*, P < 0.05 (considered significant compared with control group); **, P < 0.01 (considered highly significant); ***, P < 0.001 (considered extremely significant). 3 Results 3.1 Identification of inhibitors that target PRRSV nsp4 (3CLSP) A library of 1000 lead compounds was screened against PRRSV 3CLSP using FRET assays.
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Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus.
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