Barely Significant
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Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.

Cell · 1996 · PMC7125826 · PMID 8706132

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highly significantno p-value reported
cerevisiae have not shown highly significant amino acid sequence similarities to other proteins currently present in the public databases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.