Current Diagnosis, Treatment and Clinical Challenges in the Management of Lipodystrophy Syndromes in Children and Young People

Younger infants have higher leptin levels than older infants presumably secondary to an initial increase in breast milk leptin from colostrum to mature milk, which is followed by a decreasing trend during the first months of lactation and a subsequent increase during the late period of lactation ( 65 , 66 , 67 ).

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