a nonsignificant trendp = 0.307
OS did not significantly differ between patients treated with PCI-27483- GEM and those with GEM alone but there was a nonsignificant trend toward longer PFS in patients receiving PCI-27483- GEM compared to those receiving GEM alone (PFS: 3.7 months vs. 1.9 months; HR 0.62; p = 0.307) [ 99 ].