It is well known that the GSTM1 null and the GSTT1 null genotypes are frequent in the general population, but with significant worldwide variability [ 58 , 59 , 60 ], and their role and “relative weight” as risk factors for several dermatologic conditions may range from irrelevant to highly significant, depending on the population studied [ 10 , 11 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ].
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