Barely Significant
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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma.

Cells · 2020 · PMC7140810 · PMID 32210188

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highly significantp < 0.001actually significant
We found a highly significant overlap ( p < 0.001) of 31 genes between the 90 high confidence Wnt-regulated genes we identified previously in SK-N-BE(2)-C cells [ 16 ] and the 1331 BMP4-regulated genes ( p ≤ 0.005, DESEQ2 test, min. fold change 1.3), although 11 genes were oppositely regulated The complex interplay of BMP and Wnt signaling is also demonstrated by the strong but opposite regulation of the non-canonical Wnt ligand WNT11 ( Figure 5 B).

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