Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease.

Clin Rheumatol · 2020 · PMC7142048 · PMID 31916109

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a trend towards significanceno p-value reported

CD226 SNP rs763361 was significantly associated with SSc-ILD in a meta-analysis study of three European populations, with a trend towards significance when each population was analysed separately [ 14 ].

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