Barely Significant
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Effects of a Combination of Water-Soluble CoenzymeQ10 and Collagen on Skin Parameters and Condition:Results of a Randomised, Placebo-Controlled,Double-Blind Study.

Nutrients · 2020 · PMC7146335 · PMID 32120787

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a decreasing trendno p-value reported
Although there were no statistically significant changes in skin hydration between the treatment and placebo group after 12 weeks of supplementation, a decreasing trend for hydration was observed in both groups throughout the study period, which can be most likely attributed to seasonal variations.

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