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Advantages and Limitations of Commonly Used Nonhuman Primate Species in Research and Development of Biopharmaceuticals

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment · 2015 · PMC7149394

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a slight trendno p-value reported
The only finding associated with canakinumab treatment was a slight reduction in the number of fetuses at the high dose, which correlated with a slight trend toward decreased placental weight.

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