Medium Optimization by Response Surface Methodology for Improved Cholesterol Oxidase Production by a Newly Isolated <i>Streptomyces rochei</i> NAM-19 Strain.

Looking at the obtained p values for the model, results showed that the linear terms X 1, X 2, and X 3, all quadratic terms X 1 2 , X 2 2 , X 3 2 , and X 4 2 , and cross terms X 1 ∗ X 2, X 1 ∗ X 3, X 1 ∗ X 4, X 2 ∗ X 4, and X 3 ∗ X 4 were highly significant.

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