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Evaluations of Quality by Design (QbD) Elements Impact for Developing Niosomes as a Promising Topical Drug Delivery Platform.

Pharmaceutics · 2020 · PMC7150869 · PMID 32182792

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a decreasing trendno p-value reported
an increasing trendno p-value reported
It was observed that were was a decreasing trend in entrapment efficiency and an increasing trend in particle sizes with the increase in external phase volume above 20 mL.

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