Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels.

Two-way ANOVA revealed that both CD type (α, β, or γ) and cross linking were significantly different ( p < 0.05), with the exception of pCD at 1:0.32 and 1:0.64, which bordered on significance ( p = 0.053). pCD-β at the highest crosslinking density (1:0.64; 144.8 ± 12.1%) swelled significantly more than pCD-α (80.1 ± 5.9%) or -γ (58.9 ± 3.2%) ( p < 0.001), and, overall, pCD-β showed the smallest decrease in swelling with increasing crosslinking ( Figure 1 ). 2.2.

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