Subcutaneous allergen immunotherapy for asthma: A randomized, double-blind, placebo-controlled study with a standardized <i>Blomia tropicalis</i> vaccine.

The difference between the active and placebo groups, for the 3 cumulative scores, was highly significant p < 0.001.

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1 In Latin American, several studies confirm an increasing trend in asthma prevalence. 2 Prevalence in Cuba is also high, ranging from 8.5% to 10% of adults and up to 17.8% of children. 3 , 4 In addition, the direct and indirect costs of asthma represent a major economic burden to the Cuban health care system and society. 5 House Dust Mite (HDM) allergens are strongly involved in the pathogenesis of allergic asthma.

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