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Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?

Clin Pharmacol Ther · 2020 · PMC7158211 · PMID 31957003

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an increasing trendno p-value reported
With target prioritization in mind, there is an increasing trend to apply network (topological) methods, such as knowledge graphs ( Table 1 ), to impute novel protein‐phenotype or protein‐function associations by seeking different network paths that connect proteins/genes to specific properties. 3 One such methodology, MetaPath, 5 can be used to prioritize novel drug targets.

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