Subject demographics of included individuals are summarised in Table 1 . MRC deficiency is more pronounced in the MM1 molecular subtype of sCJD Individual assessment of MM1- and VV2 sCJD molecular subtypes showed highly significant differences in terms of MRC deficiency.
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Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease.
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