Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families.

Breast Cancer Res · 2020 · PMC7161277 · PMID 32295625

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highly significantno p-value reported

Here, we describe a patient with a germline ERBB2 variant undergoing highly significant somatic enrichment by CN-LOH.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.