Determining Whether Agonist Density or Agonist Number Is More Important for Immune Activation via Micoparticle Based Assay.

Both MPLA and Pam2 have a highly significant positive trend between number of agonists and TNFα intensity ( p < 10 –3 ) and reasonable R 2 values for the curve fit given the degree of biological variability inherent in an immune response ( Table 1 ).

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