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An Age-Period-Cohort Analysis of Stroke Mortality Attributable to Low Physical Activity in China and Japan: Data from the GBD Study 1990-2016.

Sci Rep · 2020 · PMC7162896 · PMID 32300134

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an increasing trendno p-value reported
In recent decades, the mean sex ratio of stroke mortality (men to women) experienced an increasing trend worldwide.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.