A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.

The differences in Fis and NinH motifs may not be significant and both proteins could potentially compete for the same nucleotide sequence targets [ 14 , 15 ]; Asn84 in Fis (Ser29 in NinH) makes base-specific contacts at −4/4 but the consensus sequences match at this position ( Figure 5B,C ); neither this residue nor other internal nucleotide sequences are critical for Fis binding at high-affinity sites [ 14 , 45 ].

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