Leydig-like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats.

J Cell Mol Med · 2020 · PMC7171312 · PMID 32160419

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a decreasing trendno p-value reported

The results indicated that the expression levels of steroidogenic enzymes of the iLCs group in vivo showed a decreasing trend corresponding to the trend of serum testosterone levels of castrated rats receiving iLCs transplantation.

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