Barely Significant
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Orthopaedic and brain injuries over last 10 seasons in the National Football League (NFL): number and effect on missed playing time.

BMJ Open Sport Exerc Med · 2020 · PMC7173995 · PMID 32341797

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a decreasing trendno p-value reported
Evolution of player safety in the NFL (2010–2019) Lack of a decreasing trend in the number of players with injuries to the leg, back, arm or head indicates that the NFL’s annual ritual of rule changes has had negligible long-term impact on player safety.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.