Structural basis for ion selectivity in TMEM175 K⁺ channels.

The human TMEM175 channel has been linked to Parkinson disease (PD) by several genome wide association studies and is considered as a highly significant risk gene for the early onset of this neurodegenerative disease ( Jinn et al., 2017 ; Nalls et al., 2014 ; Chang et al., 2017 ).

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