The changes of inflammatory mediators and vasoactive substances in dairy cows' plasma with pasture-associated laminitis.

We examined a total of 60 cows, including subclinical laminitis, chronic laminitis and healthy without any symptoms with 20 animals in each group. Inflammatory mediators Compared with healthy cows, HIS, IL-6, LPS, and TNF-α in subclinical laminitis group significantly increased ( P < 0.05), extremely significant increased HIS, LPS, TNF-α ( P < 0.01) as shown in (Figs. 1 , 2 , 3 , 4 , 5 ); compared with healthy cows, COX-2, HIS, IL-6, LPS, and TNF-α in chronic laminitis cows were significantly increased ( P < 0.05), extremely significant increased COX-2, HIS, TNF-α ( P < 0.01) as shown in (Figs. 1 , 2 , 3 , 4 , 5 ).

also in 7,787 other papers