The consequences of cross-regulation might be significant in chemotherapeutic contexts, given that one drug has the potential to induce the UGT pathway and create a novel form of multidrug resistance to other treatments inactivated by UGTs. 49 Clinical evidence of acquired resistance mediated by induced UGT expression in leukaemias The significant contrib
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Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression.
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