There was a highly significant and early decrease in cornea sensitivity when measured by response to a hyperosmotic solution in both rat models, but this approach did not demonstrate progression.
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Progressive Loss of Corneal Nerve Fibers and Sensitivity in Rats Modeling Obesity and Type 2 Diabetes Is Reversible with Omega-3 Fatty Acid Intervention: Supporting Cornea Analyses as a Marker for Peripheral Neuropathy and Treatment.
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