Comparison of short-term (saliva) and long-term (hair) cortisol levels in out-patients with melancholic and non-melancholic major depression.

62 We were able to confirm that there was a variance of melancholic symptoms in our sample, after finding higher levels of melancholic symptoms as defined by the Newcastle scale within our melancholic depression group, and an extremely significant positive correlation between HRSD-17 and Newcastle scale scores ( r = 0.65, P < 0.001).

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Whereas increases in HRSD-17 scores exhibited a significant and positive association with higher DELTA ( P = 0.02), only a positive trend was observed between AUCg levels in short-term saliva samples and the HRSD-17 ( P = 0.07).

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