Finally, analysis of allergen-induced IL-2, IL-4, and IL-31 production in sensitized dogs showed significant differences only in IL-4/IL-31 production (not IL-2 levels) in dogs treated with dog or human Igs ( Figure 7(a) ), which again translated to a highly significant increase in IL-2 : IL-4 and IL-2 : IL-31 ratios in the same groups ( Figure 7(b) ). 4.
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