Enhanced orbital adipogenesis in a mouse model of T-cell-mediated autoimmunity, zymosan A-treated SKG mice: Implications for Graves' ophthalmopathy.

Meanwhile, a previous study using blood samples of patients with Graves’ disease reported that a single nucleotide polymorphism within the lymphoid tyrosine phosphatase (LYP), a potent inhibitor of signal transduction and activation of T-cells, had a highly significant association with Graves’ disease compared to healthy controls 10 .

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