Major revisions: 1) Added details regarding use of Matrigel in the Methods and Results and discussed potential confounding effects of Matrigel on primary tumor volume in the Discussion 2) For data with small sample sizes showing a nonsignificant trend, revised interpretation of data to include possibility of significant differences if more mice were used 3) Expanded discussion on potential impact of ephrin-A1 deficiency on other ephrin-A1 ligands and EphA receptors in stromal cells and their signaling 4) Expanded discussion on what is known abou
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