Barely Significant
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Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma.

PLoS Genet · 2020 · PMC7199928 · PMID 32369491

Europe PMCDOI
2
hedged sentences
0.2400
closest p · 4.8× alpha
0.2400
boldest claim

The sentences

marginally significantP = 0.24not close (p > 0.1)
Collectively, these three variants showed a marginally significant association with lower one of the IOP measurements ( P = 0.24 and 0.0012 for corneal compensated and Goldman-correlated IOP, respectively, Fig 1 ), with the protein-altering allele p.Arg140His also showing a marginally significant effect on its own ( P = 1.3x10 -3 and 1.9x10 -3 for corneal compensated and Goldman-correlated IOP, respectively, Table 1 ).

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highly significantno p-value reported
S8: This PheWAS analysis isn’t mentioned anywhere in the text, except to indicate that the association of R220C with glaucoma was highly significant.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.