Genomic differentiation and intercontinental population structure of mosquito vectors Culex pipiens pipiens and Culex pipiens molestus.

The level of genomic diversity did not differ significantly between the subspecies demonstrating an overall trend of slightly lower genetic diversity in Cx. p. molestus; however, this was not significant in pairwise comparisons except for the cultivated colonies from Chicago, IL (Fig. 7 ), which demonstrated a strong depletion of genetic diversity in Cx. p. molestus .

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To get more insight into the nature of genomic differentiation between subspecies/populations, we calculated genome-wide pairwise Fst values and found that they varied between 0.08 and 0.25 and were highly significant for all comparisons (Fig. 5 ).

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