TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection.

JHEP Rep · 2020 · PMC7200939 · PMID 32382723

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highly significantno p-value reported

22 The evaluation of transcriptional changes by microarray analysis in the livers of AAV-HBV/HDV-coinfected mice (GEO accession number: GSE98342 ) revealed a highly significant activation of the expression of genes associated with IFN-γ and TNF-α signaling pathways, with Z scores of 11.25 and 9.50.

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