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Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design.

PLoS One · 2020 · PMC7205207 · PMID 32379792

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an increasing trendno p-value reported
Introduction Use of antibodies as therapeutics is an increasing trend, with over 80 currently approved in the United States and/or Europe.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.