Autophagy role(s) in response to oncogenes and DNA replication stress.

Together, and consistently with another report [ 32 ], we showed that oncogenic expression induced autophagy independently of the cell type, while the strength of DDR signalling and precise kinetics of autophagy induction were oncogene- and cell type-dependent, with an overall trend for the DDR activation to precede autophagy induction.

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