highly significantp < 0.001
In contrast, PTXF-treated NSCs underwent differentiation into the oligodendrocyte lineage, as demonstrated by a complete and highly significant shift towards OLIG2 + cells (86.67% ± 6.67%, +PTXF, nonparametric Kruskal-Wallis test, *** p < 0.001, Figure 4 E) which were not detectable in the untreated control (0%, −PTXF, Figure 4 E).