Barely Significant
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Do Adolescents Use Substances to Relieve Uncomfortable Sensations? A Preliminary Examination of Negative Reinforcement among Adolescent Cannabis and Alcohol Users.

Brain Sci · 2020 · PMC7226193 · PMID 32260480

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may not be significantno p-value reported
Overall, this could suggest that experiencing the breathing load within the context of an experimental manipulation may not be significant enough to elicit a strong insular response among adolescents.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.