Prognostic implication and functional exploration for microRNA-20a as a molecular biomarker of gastrointestinal cancer.

All the studies measured miR-20a by reverse-transcription quantitative polymerase chain reaction (RT-qPCR). Pooled prognostic value of miR-20a in gastrointestinal cancer A random-effect model was applied to generate the combined association between miR-20a expression level and overall survival of GIC patients, since highly significant heterogeneity (I 2 = 89.5%, P < 0.001) was detected when twelve studies were pooled (Fig. 2 ).

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