Barely Significant
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Twitter as a sentinel tool to monitor public opinion on vaccination: an opinion mining analysis from September 2016 to August 2017 in Italy.

Hum Vaccin Immunother · 2020 · PMC7227677 · PMID 32118519

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an increasing trendno p-value reported
During this period, we found an increasing trend in the number of tweets on this topic.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.